Tue, 07/24/2012 – 18:52 — traine

The ADAPT Trial is an observational study from Oz/NZ which looks uses TIMI 0, and negative Trop I at 0 and 2 hours as a Low Risk Chest Pain rule out.  I will direct you to 2 slightly different takes on the study below.

I will note here that I discussed this with our Chest Pain Pathway author, Dr Scheuermeyer. He ran our cohort of patients from the validation study using the ADAPT criteria.  Our study missed NO (that is zero) events.  Using the ADAPT criteria on our cohort would have resulted in six (6) missed events.

Here are the reviews of the ADAPT trial from EM Lit of Note and (the new and quite excellent) St Emlyn’s from the EM group in Manchester.

Read the paper (free at the JACC site here), and then the posts above. There is also anEditorial that accompanies the JACC paper, found here.  Please post your comments here once you have digested those.